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Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

Rohith Krishna, Jue Wang, Woody Ahern, et al.

Single-cell epigenomic reconstruction of developmental trajectories in human neural organoid systems from pluripotency

Fides Zenk, Jonas Simon Fleck, Sophie Martina Johanna Jansen, et al.

Double-strand breaks in facultative heterochromatin require specific movements and chromatin changes for efficient repair

Marieke R. Wensveen, Aditya A. Dixit, Serafin U. Colmenares, et al.

Patterned embryonic invagination evolved in response to mechanical instability

Bruno C. Vellutini, Marina B. Cuenca, Abhijeet Krishna, et al.

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Divergent evolutionary strategies preempt tissue collision in fly gastrulation

Bipasha Dey, Verena Kaul, Girish Kale, et al.

Multi-pass, single-molecule nanopore reading of long protein strands with single-amino acid sensitivity

Keisuke Motone, Daphne Kontogiorgos-Heintz, Jasmine Wee, et al.

Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery

Jayne Aiken, Erika L. F. Holzbaur

LincRNAs enable germ cells differentiation by promoting PUF proteins condensation

Roni Falk, Noa Gilad, Hanna Achache, et al.

Metabolomic profiling reveals effects of marein on energy metabolism in HepG2 cells

Baoping Jiang, Liang Le,, Keping Hu, et al.

NAD(H) homeostasis is essential for host protection mediated by glycolytic myeloid cells in tuberculosis

Hayden T. Pacl, Krishna C. Chinta, Vineel P. Reddy, et al.

The genome of the colonial hydroid Hydractinia reveals their stem cells utilize a toolkit of evolutionarily shared genes with all animals

Christine E. Schnitzler, E. Sally Chang, Justin Waletich, et al.

An oncogenic isoform of septin 9 promotes the formation of juxtanuclear invadopodia by reducing nuclear deformability

Joshua Okletey, Dimitrios Angelis, Tia M. Jones, et al.

CRISPR screens in iPSC-derived neurons reveal principles of tau proteostasis

Avi J. Samelson, Nabeela Ariqat, Justin McKetney, et al.